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control chicken immunoglobulin y  (R&D Systems)


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    R&D Systems control chicken immunoglobulin y
    Control Chicken Immunoglobulin Y, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 40 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/control chicken immunoglobulin y/product/R&D Systems
    Average 90 stars, based on 40 article reviews
    control chicken immunoglobulin y - by Bioz Stars, 2026-02
    90/100 stars

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    Blockade of the brain-derived neurotrophic factor (BDNF) signaling cascade by anti-BDNF infusion abolishes the antidepressant effects of tetramethylpyrazine (TMP). (A) Pre-infusion of an anti-BDNF antibody blocked the TMP-induced decrease of immobility in the forced swimming test in a dose-dependent manner between 5 and 20 µg/ml. (B) Pre-infusion of the anti-BDNF antibody (20 µg/ml) also prevented the TMP-induced decrease of immobility in the tail suspension test. (C) Chronic social defeat stress (CSDS)-treated mice were co-treated with TMP and anti-BDNF antibody (20 µg/ml) for 14 d. CSDS + TMP + anti-BDNF mice displayed significantly lower sucrose consumption than CSDS + TMP + <t>Immunoglobulin</t> <t>Y</t> <t>(IgY)</t> mice. (D) Co-treatment of TMP with the anti-BDNF antibody (20 µg/ml) blocked the antidepressant effect of TMP in the social interaction test. CSDS + TMP + anti-BDNF mice displayed significantly lower social interaction than CSDS + TMP + IgY mice. Results are expressed as means ± standard error of the mean (n = 10); * p < 0.05, ** p < 0.01; n.s., no significance. Comparison was made by one-way analysis of variance followed by a post hoc LSD test.
    Chicken Immunoglobulin Y (Igy) Control Ig, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    control chicken immunoglobulin y  (R&D Systems)
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    R&D Systems control chicken immunoglobulin y
    Blockade of the brain-derived neurotrophic factor (BDNF) signaling cascade by anti-BDNF infusion abolishes the antidepressant effects of tetramethylpyrazine (TMP). (A) Pre-infusion of an anti-BDNF antibody blocked the TMP-induced decrease of immobility in the forced swimming test in a dose-dependent manner between 5 and 20 µg/ml. (B) Pre-infusion of the anti-BDNF antibody (20 µg/ml) also prevented the TMP-induced decrease of immobility in the tail suspension test. (C) Chronic social defeat stress (CSDS)-treated mice were co-treated with TMP and anti-BDNF antibody (20 µg/ml) for 14 d. CSDS + TMP + anti-BDNF mice displayed significantly lower sucrose consumption than CSDS + TMP + <t>Immunoglobulin</t> <t>Y</t> <t>(IgY)</t> mice. (D) Co-treatment of TMP with the anti-BDNF antibody (20 µg/ml) blocked the antidepressant effect of TMP in the social interaction test. CSDS + TMP + anti-BDNF mice displayed significantly lower social interaction than CSDS + TMP + IgY mice. Results are expressed as means ± standard error of the mean (n = 10); * p < 0.05, ** p < 0.01; n.s., no significance. Comparison was made by one-way analysis of variance followed by a post hoc LSD test.
    Control Chicken Immunoglobulin Y, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/control chicken immunoglobulin y/product/R&D Systems
    Average 90 stars, based on 1 article reviews
    control chicken immunoglobulin y - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier

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    Blockade of the brain-derived neurotrophic factor (BDNF) signaling cascade by anti-BDNF infusion abolishes the antidepressant effects of tetramethylpyrazine (TMP). (A) Pre-infusion of an anti-BDNF antibody blocked the TMP-induced decrease of immobility in the forced swimming test in a dose-dependent manner between 5 and 20 µg/ml. (B) Pre-infusion of the anti-BDNF antibody (20 µg/ml) also prevented the TMP-induced decrease of immobility in the tail suspension test. (C) Chronic social defeat stress (CSDS)-treated mice were co-treated with TMP and anti-BDNF antibody (20 µg/ml) for 14 d. CSDS + TMP + anti-BDNF mice displayed significantly lower sucrose consumption than CSDS + TMP + Immunoglobulin Y (IgY) mice. (D) Co-treatment of TMP with the anti-BDNF antibody (20 µg/ml) blocked the antidepressant effect of TMP in the social interaction test. CSDS + TMP + anti-BDNF mice displayed significantly lower social interaction than CSDS + TMP + IgY mice. Results are expressed as means ± standard error of the mean (n = 10); * p < 0.05, ** p < 0.01; n.s., no significance. Comparison was made by one-way analysis of variance followed by a post hoc LSD test.

    Journal: International Journal of Neuropsychopharmacology

    Article Title: Tetramethylpyrazine Produces Antidepressant-Like Effects in Mice Through Promotion of BDNF Signaling Pathway

    doi: 10.1093/ijnp/pyv010

    Figure Lengend Snippet: Blockade of the brain-derived neurotrophic factor (BDNF) signaling cascade by anti-BDNF infusion abolishes the antidepressant effects of tetramethylpyrazine (TMP). (A) Pre-infusion of an anti-BDNF antibody blocked the TMP-induced decrease of immobility in the forced swimming test in a dose-dependent manner between 5 and 20 µg/ml. (B) Pre-infusion of the anti-BDNF antibody (20 µg/ml) also prevented the TMP-induced decrease of immobility in the tail suspension test. (C) Chronic social defeat stress (CSDS)-treated mice were co-treated with TMP and anti-BDNF antibody (20 µg/ml) for 14 d. CSDS + TMP + anti-BDNF mice displayed significantly lower sucrose consumption than CSDS + TMP + Immunoglobulin Y (IgY) mice. (D) Co-treatment of TMP with the anti-BDNF antibody (20 µg/ml) blocked the antidepressant effect of TMP in the social interaction test. CSDS + TMP + anti-BDNF mice displayed significantly lower social interaction than CSDS + TMP + IgY mice. Results are expressed as means ± standard error of the mean (n = 10); * p < 0.05, ** p < 0.01; n.s., no significance. Comparison was made by one-way analysis of variance followed by a post hoc LSD test.

    Article Snippet: Chicken anti-BDNF neutralizing antibody and chicken Immunoglobulin Y (IgY) control Ig were purchased from Promega.

    Techniques: Derivative Assay

    Anti-BDNF (brain-derived neurotrophic factor) infusion blocks the neurogenic effects of tetramethylpyrazine (TMP). (A) Representative confocal microscopic images show the staining of doublecortin (DCX; green) in the dentate granule cell layer. The scale bar is 200 µm for representative images and 50 µm for enlarged images, respectively. Density statistics showed that the increased number of DCX positive cells induced by TMP was blocked by anti-BDNF infusion. (B) Representative microscopic images showed the co-staining (yellow) of Neuronal Nuclei (NeuN) (green) and 5-Bromo-2-deoxyUridine (Brdu) (red) in the dentate gyrus (DG). The scale bar is 100 µm. Density statistics showed that co-injection with the anti-BDNF antibody blocked the TMP effects on the amount of NeuN+/Brdu+ cells in the DG. Data are expressed as means ± standard error of the mean (n = 5); * p < 0.01; n.s., no significance. Comparison was made by one-way analysis of variance followed by a post hoc LSD test. CSDS, chronic social defeat stress; Immunoglobulin Y (IgY).

    Journal: International Journal of Neuropsychopharmacology

    Article Title: Tetramethylpyrazine Produces Antidepressant-Like Effects in Mice Through Promotion of BDNF Signaling Pathway

    doi: 10.1093/ijnp/pyv010

    Figure Lengend Snippet: Anti-BDNF (brain-derived neurotrophic factor) infusion blocks the neurogenic effects of tetramethylpyrazine (TMP). (A) Representative confocal microscopic images show the staining of doublecortin (DCX; green) in the dentate granule cell layer. The scale bar is 200 µm for representative images and 50 µm for enlarged images, respectively. Density statistics showed that the increased number of DCX positive cells induced by TMP was blocked by anti-BDNF infusion. (B) Representative microscopic images showed the co-staining (yellow) of Neuronal Nuclei (NeuN) (green) and 5-Bromo-2-deoxyUridine (Brdu) (red) in the dentate gyrus (DG). The scale bar is 100 µm. Density statistics showed that co-injection with the anti-BDNF antibody blocked the TMP effects on the amount of NeuN+/Brdu+ cells in the DG. Data are expressed as means ± standard error of the mean (n = 5); * p < 0.01; n.s., no significance. Comparison was made by one-way analysis of variance followed by a post hoc LSD test. CSDS, chronic social defeat stress; Immunoglobulin Y (IgY).

    Article Snippet: Chicken anti-BDNF neutralizing antibody and chicken Immunoglobulin Y (IgY) control Ig were purchased from Promega.

    Techniques: Derivative Assay, Staining, Injection